

ARA-290 16mg
$79.99
Eleven-residue helix-B surface peptide of erythropoietin, studied at the innate repair receptor without erythropoietic signalling. Research use only.
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Pairs with every vialISLA-H20 10mLBacteriostatic water for reconstitution$19.99Identity
ARA-290, also called cibinetide, is an 11-residue linear peptide corresponding to the aqueous face of helix B of erythropoietin. That face of the parent molecule is the surface that does not contact the classical erythropoietin receptor homodimer, which is the basis of the whole design.
Molecular target
The innate repair receptor, a heterocomplex of the erythropoietin receptor with the beta-common receptor CD131, the subunit shared with the GM-CSF, IL-3 and IL-5 receptors. Because the peptide does not engage the EPOR homodimer, it is used in models where erythropoiesis and haematocrit change would be confounders.
Signalling pathway
Engagement of the heterocomplex activates JAK2 with downstream STAT3 and PI3K/Akt signalling. The published readouts are anti-apoptotic and anti-inflammatory rather than haematopoietic, studied in tissue under metabolic or ischaemic stress.
Research context
Rodent nerve-injury, ischaemia and inflammation models. Small human trials exist in sarcoidosis-associated small fibre neuropathy, which is unusual for a compound in this catalogue.
Specification
- Form: lyophilised powder, sealed vial
- Purity: verified by high-performance liquid chromatography with mass spectrometric confirmation
- Analysis: third-party tested, full report published against the batch number on the vial
- Storage: 2-8 °C
Handling: See our step-by-step reconstitution protocol, and our guide to bacteriostatic water vs sterile water for choosing a diluent.
For laboratory research use only. Not for human or veterinary use.
- 16mg99.8%purity by HPLCView certificate
Important
- ISLA-H20 sold separately
- Syringes not included
- Supplied as lyophilised powder
- Third-party tested, every batch
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All products are supplied strictly for in-vitro laboratory research purposes only. Not for human consumption, medical, or veterinary use. Isla Longevity does not condone the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution and are at least 21 years old.
? Details
Intended Use: Supplied for laboratory research purposes only. All peptides require reconstitution with ISLA-H20, sold separately.
Form: Lyophilised (freeze-dried) powder in a sealed sterile vial.
Storage: Store the vial in a cool, dry place away from direct light. Once reconstituted, keep refrigerated at 2–8°C and use within the recommended timeframe.
Solubility: Reconstitute with ISLA-H20. Avoid repeated freeze–thaw cycles to preserve integrity.
Testing: Every batch is independently analysed by Bioviridian for identity (LC-MS) and purity (HPLC), with the certificate published in our COA Bank.
Independent Lab Testing
Verified by Bioviridian
Certificates from our current batches. Every batch is analysed by an independent laboratory for identity (LC-MS) and purity (HPLC), and the full report is published in our COA Bank.
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