
SNAP-8 10mg
$39.99
Acetyl octapeptide-3, a SNAP-25 N-terminal mimetic studied for competitive interference with SNARE complex assembly. Research use only.
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Pairs with every vialISLA-H20 10mLBacteriostatic water for reconstitution$19.99Identity
SNAP-8 is acetyl octapeptide-3, also listed as acetyl glutamyl heptapeptide-3. It is an eight-residue elongation of acetyl hexapeptide-8 (Argireline), and its sequence mimics the N-terminal end of SNAP-25.
Molecular target
The SNARE complex. Rather than binding a receptor, the peptide competes with native SNAP-25 for its position in the ternary SNARE assembly formed with syntaxin and VAMP.
Signalling pathway
A SNARE complex that incorporates the mimetic in place of SNAP-25 is less competent to dock and fuse secretory vesicles. The reported consequence in chromaffin-cell preparations is reduced calcium-dependent catecholamine exocytosis, and the same mechanism is the basis for the compound being studied at the neuromuscular junction.
Research context
Bovine chromaffin cell culture and in vitro cosmetic-science assays. The published evidence is in vitro; the two extra residues relative to Argireline were introduced for solubility and formulation behaviour rather than on mechanistic grounds.
Specification
- Form: lyophilised powder, sealed vial
- Purity: verified by high-performance liquid chromatography with mass spectrometric confirmation
- Analysis: third-party tested, full report published against the batch number on the vial
- Storage: 2-8 °C
Handling: See our step-by-step reconstitution protocol, and our guide to bacteriostatic water vs sterile water for choosing a diluent.
For laboratory research use only. Not for human or veterinary use.
Important
- ISLA-H20 sold separately
- Syringes not included
- Supplied as lyophilised powder
- Third-party tested, every batch
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All products are supplied strictly for in-vitro laboratory research purposes only. Not for human consumption, medical, or veterinary use. Isla Longevity does not condone the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution and are at least 21 years old.
? Details
Intended Use: Supplied for laboratory research purposes only. All peptides require reconstitution with ISLA-H20, sold separately.
Form: Lyophilised (freeze-dried) powder in a sealed sterile vial.
Storage: Store the vial in a cool, dry place away from direct light. Once reconstituted, keep refrigerated at 2–8°C and use within the recommended timeframe.
Solubility: Reconstitute with ISLA-H20. Avoid repeated freeze–thaw cycles to preserve integrity.
Testing: Every batch is independently analysed by Freedom Diagnostics, with certificates of analysis published openly.
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