TB500 10mg

Name: TB500 10mg
Brand: Isla Longevity
SKU: TB500-10MG
Price: 89.99 USD
Availability: InStock

$89.99

Synthetic fragment of thymosin beta-4 carrying the actin-binding motif, studied in cytoskeletal remodelling and cell migration. Research use only.

Add 2 more to unlock 5% off

Bulk pricingapplied automatically in cart

Spend $250+ for free priority shipping

Est. delivery2–3 daysThird-partytestedSame-daydispatch

Pairs with every vialISLA-H20 10mLBacteriostatic water for reconstitution$19.99

Secured PaymentVISAMCAMEXG Pay

Guaranteed Fast Delivery

Third-party testedCOA on every batch

Made in the USASynthesized & shipped from the US

Same-day dispatchUPS · 2–3 days · free over $250

Money-back guaranteeSee our refund policy

Secure checkoutPay the way you like

ZelleVenmoCash AppCard

Lab certificate · COA1037399.8% purity · Bioviridian · May 2026

View COA

SKU: TB500-10MG Category: Repair & Signalling Lab certificates: View in the COA Bank

Product Overview

Identity

TB-500 is a synthetic peptide corresponding to the actin-binding region of thymosin beta-4, a 43-residue G-actin-sequestering protein found in most mammalian cells. The supplied material is the acetylated fragment built around the LKKTETQ motif at residues 17-23 of the parent sequence, which is the portion that carries actin-binding activity.

Molecular target

No cell-surface receptor has been established for this fragment. The LKKTETQ motif binds monomeric G-actin directly, forming a one-to-one complex, so the target is a cytoskeletal protein rather than a membrane receptor.

Signalling pathway

Sequestering G-actin shifts the equilibrium between monomeric and filamentous actin. Published work has examined the downstream consequences for cytoskeletal reorganisation, directed cell migration and the transcription of matrix and angiogenic genes, including MRTF/SRF-dependent transcription that is itself sensitive to the free G-actin pool.

Research context

Endothelial, fibroblast and cardiomyocyte culture, and rodent injury models. In vitro and preclinical evidence only.

Specification

Form: lyophilised powder, sealed vial
Purity: verified by high-performance liquid chromatography with mass spectrometric confirmation
Analysis: third-party tested, full report published against the batch number on the vial
Storage: 2-8 °C

Handling: See our step-by-step reconstitution protocol, and our guide to bacteriostatic water vs sterile water for choosing a diluent.

For laboratory research use only. Not for human or veterinary use.

Specifications

All certificates in the COA Bank →

FormatLyophilised powderSealed vial

Endotoxin<0.05 EU/mlLAL test

Third-party analysis, by batch

10mg99.8%purity by HPLCBioviridian · Report COA10373 · May 2026View certificate

In-vitro laboratory research only. Not for human or veterinary use.

Important

ISLA-H20 sold separately
Syringes not included
Supplied as lyophilised powder
Third-party tested, every batch

Money-Back Guarantee

14-day return policy

Third-Party Tested

Bioviridian verified, every batch

Customer Support

Real people, real answers

Fast US Shipping

Same-day dispatch

All products are supplied strictly for in-vitro laboratory research purposes only. Not for human consumption, medical, or veterinary use. Isla Longevity does not condone the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution and are at least 21 years old.

? Details

Intended Use: Supplied for laboratory research purposes only. All peptides require reconstitution with ISLA-H20, sold separately.

Form: Lyophilised (freeze-dried) powder in a sealed sterile vial.

Storage: Store the vial in a cool, dry place away from direct light. Once reconstituted, keep refrigerated at 2–8°C and use within the recommended timeframe.

Solubility: Reconstitute with ISLA-H20. Avoid repeated freeze–thaw cycles to preserve integrity.

Testing: Every batch is independently analysed by Bioviridian for identity (LC-MS) and purity (HPLC), with the certificate published in our COA Bank.

Independent Lab Testing

Verified by Bioviridian

Certificates from our current batches. Every batch is analysed by an independent laboratory for identity (LC-MS) and purity (HPLC), and the full report is published in our COA Bank.