5-Amino 1MQ 50mg

Name: 5-Amino 1MQ 50mg
Brand: Isla Longevity
SKU: 5-AMINO-1MQ-50MG
Price: 119.99 USD
Availability: InStock

$119.99

Small-molecule inhibitor of nicotinamide N-methyltransferase, studied in NAD+ salvage and methyl-pool metabolism. Research use only.

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Pairs with every vialISLA-H20 10mLBacteriostatic water for reconstitution$19.99

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Lab certificate · COA1037199.8% purity · Bioviridian · Jul 2026

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SKU: 5-AMINO-1MQ-50MG Category: Metabolic & GLP Lab certificates: View in the COA Bank

Product Overview

Identity

5-Amino-1MQ is 5-amino-1-methylquinolinium, a cell-permeable small-molecule quinolinium salt. It is not a peptide and is supplied as a dry powder.

Molecular target

Nicotinamide N-methyltransferase, a cytosolic enzyme that transfers a methyl group from S-adenosylmethionine to nicotinamide, producing 1-methylnicotinamide. NNMT is highly expressed in adipose tissue and liver.

Signalling pathway

Inhibiting the enzyme has two linked consequences that the literature examines separately. Nicotinamide that would otherwise be methylated and excreted remains available to the NAD+ salvage pathway, and the SAM methyl pool is spared for histone and DNA methylation reactions. Published mouse work using adipocyte NNMT knockdown reported changes in fat mass without a change in food intake.

Research context

3T3-L1 adipocyte culture and diet-induced-obese mouse models. Preclinical only.

Specification

Form: powder, sealed vial
Purity: verified by high-performance liquid chromatography with mass spectrometric confirmation
Analysis: third-party tested, full report published against the batch number on the vial
Storage: 2-8 °C

Handling: See our step-by-step reconstitution protocol, and our guide to bacteriostatic water vs sterile water for choosing a diluent.

For laboratory research use only. Not for human or veterinary use.

Specifications

All certificates in the COA Bank →

FormatLyophilised powderSealed vial

Endotoxin<0.05 EU/mlLAL test

Third-party analysis, by batch

50mg99.8%purity by HPLCBioviridian · Report COA10371 · Jul 2026View certificate

In-vitro laboratory research only. Not for human or veterinary use.

Important

ISLA-H20 sold separately
Syringes not included
Supplied as lyophilised powder
Third-party tested, every batch

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All products are supplied strictly for in-vitro laboratory research purposes only. Not for human consumption, medical, or veterinary use. Isla Longevity does not condone the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution and are at least 21 years old.

? Details

Intended Use: Supplied for laboratory research purposes only. All peptides require reconstitution with ISLA-H20, sold separately.

Form: Lyophilised (freeze-dried) powder in a sealed sterile vial.

Storage: Store the vial in a cool, dry place away from direct light. Once reconstituted, keep refrigerated at 2–8°C and use within the recommended timeframe.

Solubility: Reconstitute with ISLA-H20. Avoid repeated freeze–thaw cycles to preserve integrity.

Testing: Every batch is independently analysed by Bioviridian for identity (LC-MS) and purity (HPLC), with the certificate published in our COA Bank.

Independent Lab Testing

Verified by Bioviridian

Certificates from our current batches. Every batch is analysed by an independent laboratory for identity (LC-MS) and purity (HPLC), and the full report is published in our COA Bank.