
Pancragen 20mg
$69.99
Khavinson tetrapeptide Lys-Glu-Asp-Trp, studied in pancreatic islet and glucose-metabolism models. Research use only.
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Pairs with every vialISLA-H20 10mLBacteriostatic water for reconstitution$19.99Identity
Pancragen is the tetrapeptide Lys-Glu-Asp-Trp (KEDW), the member of the Khavinson series assigned to pancreatic tissue. The terminal tryptophan makes it one of the few members of the series with an aromatic residue, which is relevant to the spectroscopic methods used to study its DNA binding.
Molecular target
No receptor. The series is proposed to act by entering the nucleus and binding at specific promoter sequences and to histone proteins.
Signalling pathway
The published readouts for this peptide are in pancreatic islet and beta-cell preparations, where the reported outcome is changed expression of insulin and of transcription factors associated with beta-cell identity. The tryptophan residue has been used as an intrinsic fluorophore in binding studies, so the DNA-interaction evidence for this member is somewhat more direct than for others.
Research context
Pancreatic cell culture and rodent models. Preclinical only; no human trial data exists for this peptide.
Specification
- Form: lyophilised powder, sealed vial
- Purity: verified by high-performance liquid chromatography with mass spectrometric confirmation
- Analysis: third-party tested, full report published against the batch number on the vial
- Storage: 2-8 °C
Handling: See our step-by-step reconstitution protocol, and our guide to bacteriostatic water vs sterile water for choosing a diluent.
For laboratory research use only. Not for human or veterinary use.
Important
- ISLA-H20 sold separately
- Syringes not included
- Supplied as lyophilised powder
- Third-party tested, every batch
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All products are supplied strictly for in-vitro laboratory research purposes only. Not for human consumption, medical, or veterinary use. Isla Longevity does not condone the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution and are at least 21 years old.
? Details
Intended Use: Supplied for laboratory research purposes only. All peptides require reconstitution with ISLA-H20, sold separately.
Form: Lyophilised (freeze-dried) powder in a sealed sterile vial.
Storage: Store the vial in a cool, dry place away from direct light. Once reconstituted, keep refrigerated at 2–8°C and use within the recommended timeframe.
Solubility: Reconstitute with ISLA-H20. Avoid repeated freeze–thaw cycles to preserve integrity.
Testing: Every batch is independently analysed by Bioviridian for identity (LC-MS) and purity (HPLC), with the certificate published in our COA Bank.
Independent Lab Testing
Verified by Bioviridian
Certificates from our current batches. Every batch is analysed by an independent laboratory for identity (LC-MS) and purity (HPLC), and the full report is published in our COA Bank.
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