
Ipamorelin 10mg
$59.99
Pentapeptide ghrelin receptor agonist studied for growth hormone release without concurrent cortisol or prolactin signalling. Research use only.
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Pairs with every vialISLA-H20 10mLBacteriostatic water for reconstitution$19.99Identity
Ipamorelin is the synthetic pentapeptide Aib-His-D-2-Nal-D-Phe-Lys-NH2, developed after the earlier growth hormone secretagogues GHRP-6 and GHRP-2.
Molecular target
The growth hormone secretagogue receptor GHS-R1a, a Gq-coupled receptor expressed on anterior pituitary somatotrophs and in the hypothalamus. This is the receptor for endogenous ghrelin, and is distinct from the GHRH receptor targeted by sermorelin and CJC-1295.
Signalling pathway
Agonism at GHS-R1a activates phospholipase C, raising inositol trisphosphate and intracellular calcium in somatotrophs. In the animal literature ipamorelin is described as selective because that release occurred without the rise in ACTH, cortisol and prolactin seen with the earlier secretagogues. Because it acts at a separate receptor from GHRH, the two classes are frequently studied together to examine additive release.
Research context
Pituitary cell culture, rat and swine models. Preclinical; human development was discontinued after phase II.
Specification
- Form: lyophilised powder, sealed vial
- Purity: verified by high-performance liquid chromatography with mass spectrometric confirmation
- Analysis: third-party tested, full report published against the batch number on the vial
- Storage: 2-8 °C
Handling: See our step-by-step reconstitution protocol, and our guide to bacteriostatic water vs sterile water for choosing a diluent.
For laboratory research use only. Not for human or veterinary use.
Important
- ISLA-H20 sold separately
- Syringes not included
- Supplied as lyophilised powder
- Third-party tested, every batch
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All products are supplied strictly for in-vitro laboratory research purposes only. Not for human consumption, medical, or veterinary use. Isla Longevity does not condone the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution and are at least 21 years old.
? Details
Intended Use: Supplied for laboratory research purposes only. All peptides require reconstitution with ISLA-H20, sold separately.
Form: Lyophilised (freeze-dried) powder in a sealed sterile vial.
Storage: Store the vial in a cool, dry place away from direct light. Once reconstituted, keep refrigerated at 2–8°C and use within the recommended timeframe.
Solubility: Reconstitute with ISLA-H20. Avoid repeated freeze–thaw cycles to preserve integrity.
Testing: Every batch is independently analysed by Freedom Diagnostics, with certificates of analysis published openly.
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