
PT-141 10mg
$79.99
Cyclic heptapeptide melanocortin analogue studied at the central MC3R and MC4R receptors. Research use only.
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Pairs with every vialISLA-H20 10mLBacteriostatic water for reconstitution$19.99Identity
PT-141, also called bremelanotide, is a cyclic heptapeptide melanocortin analogue. It is the major metabolite of melanotan II, differing from it by the loss of the C-terminal amide.
Molecular target
The melanocortin receptor family, with the studied activity at MC3R and MC4R and weaker activity at MC1R. The shift away from MC1R relative to its parent compound is the point of pharmacological interest, MC1R being the receptor associated with pigmentation.
Signalling pathway
The melanocortin receptors are Gs-coupled, so agonism raises cyclic AMP and activates protein kinase A. In the rodent literature the effects of interest were localised to hypothalamic and spinal circuits rather than to peripheral tissue, which is why the compound is used in central-nervous-system rather than dermatological models.
Research context
Receptor binding and functional assays, and rodent behavioural and neurophysiology models. A substantial clinical literature exists under its development name.
Specification
- Form: lyophilised powder, sealed vial
- Purity: verified by high-performance liquid chromatography with mass spectrometric confirmation
- Analysis: third-party tested, full report published against the batch number on the vial
- Storage: 2-8 °C
Handling: See our step-by-step reconstitution protocol, and our guide to bacteriostatic water vs sterile water for choosing a diluent.
For laboratory research use only. Not for human or veterinary use.
Important
- ISLA-H20 sold separately
- Syringes not included
- Supplied as lyophilised powder
- Third-party tested, every batch
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All products are supplied strictly for in-vitro laboratory research purposes only. Not for human consumption, medical, or veterinary use. Isla Longevity does not condone the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution and are at least 21 years old.
? Details
Intended Use: Supplied for laboratory research purposes only. All peptides require reconstitution with ISLA-H20, sold separately.
Form: Lyophilised (freeze-dried) powder in a sealed sterile vial.
Storage: Store the vial in a cool, dry place away from direct light. Once reconstituted, keep refrigerated at 2–8°C and use within the recommended timeframe.
Solubility: Reconstitute with ISLA-H20. Avoid repeated freeze–thaw cycles to preserve integrity.
Testing: Every batch is independently analysed by Bioviridian for identity (LC-MS) and purity (HPLC), with the certificate published in our COA Bank.
Independent Lab Testing
Verified by Bioviridian
Certificates from our current batches. Every batch is analysed by an independent laboratory for identity (LC-MS) and purity (HPLC), and the full report is published in our COA Bank.
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